清脆的
回文
质粒
机制(生物学)
DNA
Cas9
核酸内切酶
生物
遗传学
计算生物学
核糖核酸
基因
物理
量子力学
出处
期刊:Annual Review of Biophysics and Biomolecular Structure
[Annual Reviews]
日期:1992-06-01
卷期号:21 (1): 441-483
被引量:862
标识
DOI:10.1146/annurev.bb.21.060192.002301
摘要
Many bacterial clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated (Cas) systems employ the dual RNA–guided DNA endonuclease Cas9 to defend against invading phages and conjugative plasmids by introducing site-specific ...Read More
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