CDKN2A
突变体
胶质瘤
IDH1
癌症研究
生物
遗传学
基因
作者
Franziska Maria Ippen,Thomas Hielscher,Dennis Friedel,Kirsten Göbel,David L. Reuss,Christel Herold‐Mende,Sandro M. Krieg,Andreas von Deimling,Wolfgang Wick,Felix Sahm,Abigail Suwala
出处
期刊:Neuro-oncology
[Oxford University Press]
日期:2024-11-12
标识
DOI:10.1093/neuonc/noae238
摘要
Homozygous deletions of CDKN2A/B are known to predict poor prognosis in gliomas, but the impact of hemizygous deletions is less clear. This study aimed to evaluate the prognostic significance of hemizygous CDKN2A/B deletions in IDH-mutant low-grade astrocytomas and oligodendrogliomas.
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