作者
Lei Zhu,Dongju Zhao,Fan Yang,Caihua Ye,Ziyao Chen,Yihan Chen,Xiaomeng Yu,Jiyao Xie,Yan Dou,Jin Chang
摘要
InfoMetricsFiguresRef. ACS NanoASAPArticle This publication is free to access through this site. Learn More CiteCitationCitation and abstractCitation and referencesMore citation options ShareShare onFacebookX (Twitter)WeChatLinkedInRedditEmailJump toExpandCollapse ORIGINAL ARTICLE. This notice is a correction.Addition/CorrectionNovember 5, 2024Correction to "In Situ Self-Assembled Phytopolyphenol-Coordinated Intelligent Nanotherapeutics for Multipronged Management of Ferroptosis-Driven Alzheimer's Disease"Click to copy article linkArticle link copied!Yining LiuYining LiuMore by Yining LiuDongju ZhaoDongju ZhaoMore by Dongju Zhaohttps://orcid.org/0000-0002-0589-5670Fan YangFan YangMore by Fan YangCaihua YeCaihua YeMore by Caihua YeZiyao ChenZiyao ChenMore by Ziyao ChenYihan ChenYihan ChenMore by Yihan ChenXiaomeng YuXiaomeng YuMore by Xiaomeng YuJiyao XieJiyao XieMore by Jiyao XieYan Dou*Yan DouMore by Yan Douhttps://orcid.org/0000-0002-6905-2787Jin Chang*Jin ChangMore by Jin Changhttps://orcid.org/0000-0002-6752-8526Open PDFACS NanoCite this: ACS Nano 2024, XXXX, XXX, XXX-XXXClick to copy citationCitation copied!https://pubs.acs.org/doi/10.1021/acsnano.4c14642https://doi.org/10.1021/acsnano.4c14642Published November 5, 2024 Publication History Received 16 October 2024Published online 5 November 2024correction© 2024 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissionsThis publication is licensed for personal use by The American Chemical Society. ACS Publications© 2024 American Chemical SocietyIn the original version of this article, Figure 3e contains the mistaken overlaying of the picture from the FAC group due to an insertion error during image assembly. This error was noticed by the authors during regular inspection of the published raw data but does not affect the results or conclusions of this article. The authors apologize for any confusion. The correct Figure 3e is reproduced here.Figure 3Figure 3. Neuroprotective effects of TQCN via inhibiting iron overload-induced oxidative stress and mitochondrial dysfunction. (a) Schematic representation of mitochondria as the site of ROS initiation by iron ions. (b) Iron content detection in HT22 cells after various treatments. (c) Representative confocal fluorescence images of DCFH-DA staining and (d) quantitative analysis. Scale bars, 20 μm. (e) Representative confocal fluorescence images of Mito-SOX staining and (f) quantitative analysis. Scale bars, 20 μm. (g) Schematic representation of iron overload-induced mitochondrial and neuronal damage rescued by TQCN. (h) Representative confocal fluorescence images of JC-10 staining and (i) quantitative analysis. Red, JC-10 aggregates. Green, JC-10 monomers. Scale bars, 100 μm. (j) Representative TEM images of mitochondrial morphology in HT22 cells after various treatments. Red arrows indicate mitochondria. Scale bars, 500 nm. (k) Flow cytometry analysis of neuronal apoptosis after various treatments and (l) quantitative statistics of apoptosis rate. FAC: 600 μmol L–1. QCN/TQCN: 25 μmol L–1. Data are presented as mean ± SD (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; ns, not significant.High Resolution ImageDownload MS PowerPoint SlideAuthor InformationClick to copy section linkSection link copied!Corresponding AuthorsYan Dou; https://orcid.org/0000-0002-6905-2787; Email: Jin Chang; https://orcid.org/0000-0002-6752-8526; Email: AuthorsYining LiuDongju Zhao; https://orcid.org/0000-0002-0589-5670Fan YangCaihua YeZiyao ChenYihan ChenXiaomeng YuJiyao XieCited By Click to copy section linkSection link copied!This article has not yet been cited by other publications.Download PDFFiguresReferences Get e-AlertsGet e-AlertsACS NanoCite this: ACS Nano 2024, XXXX, XXX, XXX-XXXClick to copy citationCitation copied!https://doi.org/10.1021/acsnano.4c14642Published November 5, 2024 Publication History Received 16 October 2024Published online 5 November 2024© 2024 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissionsArticle Views-Altmetric-Citations-Learn about these metrics closeArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated.Recommended Articles FiguresReferencesFigure 3Figure 3. Neuroprotective effects of TQCN via inhibiting iron overload-induced oxidative stress and mitochondrial dysfunction. (a) Schematic representation of mitochondria as the site of ROS initiation by iron ions. (b) Iron content detection in HT22 cells after various treatments. (c) Representative confocal fluorescence images of DCFH-DA staining and (d) quantitative analysis. Scale bars, 20 μm. (e) Representative confocal fluorescence images of Mito-SOX staining and (f) quantitative analysis. Scale bars, 20 μm. (g) Schematic representation of iron overload-induced mitochondrial and neuronal damage rescued by TQCN. (h) Representative confocal fluorescence images of JC-10 staining and (i) quantitative analysis. Red, JC-10 aggregates. Green, JC-10 monomers. Scale bars, 100 μm. (j) Representative TEM images of mitochondrial morphology in HT22 cells after various treatments. Red arrows indicate mitochondria. Scale bars, 500 nm. (k) Flow cytometry analysis of neuronal apoptosis after various treatments and (l) quantitative statistics of apoptosis rate. FAC: 600 μmol L–1. QCN/TQCN: 25 μmol L–1. Data are presented as mean ± SD (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; ns, not significant.High Resolution ImageDownload MS PowerPoint SlideThis publication has no References.