RNA沉默
核糖核酸
RNA甲基化
RNA编辑
甲基化
胞嘧啶
线粒体DNA
生物
线粒体
分子生物学
甲基转移酶
细胞生物学
化学
基因
生物化学
RNA干扰
作者
Emeline Recazens,Alexis A. Jourdain
标识
DOI:10.1016/j.tibs.2024.08.001
摘要
Mitochondrial double-stranded RNA (dsRNA) can form spontaneously in mitochondria, blocking mitochondrial gene expression and triggering an immune response. A recent study by Kim, Tan, et al. identified a safeguard mechanism in which NOP2/Sun RNA methyltransferase 4 (NSUN4)-mediated RNA methylation (m
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