神经科学
内大麻素系统
记忆巩固
海马体
突触可塑性
大麻素
压力对记忆的影响
情景记忆
记忆形成
变质塑性
心理学
生物
认知
生物化学
受体
作者
Antonio Figueiredo,Joseph F. Cheer
标识
DOI:10.1016/j.expneurol.2023.114384
摘要
Over the past few decades, tremendous work has been dedicated to understanding how cannabinoids, both endogenous and exogenous, impact the process of learning and memory. Here we attempt to summarize the breadth of this research investigating the role of cannabinoid signaling on episodic or hippocampus-dependent memory. This review will focus primarily on studies using pharmacological approaches, allowing us to discuss the impact of cannabinoids at different phases of the memory formation process. We will briefly provide an overview of the endocannabinoid system and the mechanisms underlying memory formation, then discuss the impact of cannabinoids on memory encoding, consolidation, retrieval, and extinction. Additionally, we examine the impact of cannabinoids on synaptic plasticity and intracellular signaling within the hippocampus related to these processes.
科研通智能强力驱动
Strongly Powered by AbleSci AI