材料科学
镁
多孔性
生物相容性
脚手架
镁合金
降级(电信)
复合材料
抗压强度
生物医学工程
冶金
计算机科学
医学
电信
作者
Chaoxin Wang,Shuyuan Min,Jinge Liu,Bing Liu,Bo Peng,Wei Wang,Xiaolin Ma,Peng Wen,Yufeng Zheng,Yun Tian
标识
DOI:10.1016/j.jma.2023.08.016
摘要
Only a few studies have examined how pore geometry affects the mechanical characteristics, biological behavior, and degradation of additively manufactured biodegradable porous magnesium. In this work, the effects of pore geometry on mechanical qualities, degradation, and biological behavior were investigated using three typical porous architectures with the same porosity. The porous structures were found to satisfy bone tissue engineering requirements because they had sufficient degradation resistance and tunable compressive characteristics. All three types of magnesium alloy scaffolds exhibited good biocompatibility. Additionally, the magnesium alloy porous structures influenced the magnesium scaffold material degradation rate and the surrounding environment, impacting the osteogenic differentiation of bone mesenchymal stem cells and bone tissue regeneration. This work offers conceptual support for optimizing pore geometry to alter the mechanical and degradable characteristics of additively manufactured porous magnesium to meet therapeutic demands.
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