[Advances of spatial omics in the individualized diagnosis and treatment of head and neck cancer].

Spatialomics is another research hotspot of biotechnology after single-cell sequencing technology, which can make up for the defect that single-cell sequencing technology can not obtain cell spatial distribution information. Spatialomics mainly studies the relative position of cells in tissue samples to reveal the effect of cell spatial distribution on diseases. In recent years, spatialomics has made new progress in the pathogenesis, target exploration, drug development and many other aspects of head and neck tumors. This paper summarizes the latest progress of spatialomics in the diagnosis and treatment of head and neck cancer.摘要: 空间组学是继单细胞测序技术之后的另一个生物技术研究热点，其能够弥补单细胞测序技术无法获取细胞空间分布信息的缺陷。空间组学主要研究细胞在组织样品中的相对位置关系，以揭示细胞空间分布关系对疾病的影响。近年来，空间组学在头颈肿瘤的发生机制、靶点探索、药物研发等诸多方面有了新的进展，本文围绕空间组学技术在头颈肿瘤诊疗多方面的最新进展做一概述。.