Damage control resuscitation in adult trauma patients: What you need to know

复苏 医学 重症监护医学 凝血病 损伤控制 医疗急救 损伤控制手术 失血性休克 止血 血液制品 输血 急诊医学 外科
作者
Daniel Lammers,John B. Holcomb
出处
期刊:The journal of trauma and acute care surgery [Ovid Technologies (Wolters Kluwer)]
卷期号:95 (4): 464-471 被引量:21
标识
DOI:10.1097/ta.0000000000004103
摘要

Death after injury is a worldwide epidemic. Hemorrhage as a cause of death represents the leading potentially preventable condition. Based on hard-won experience from the recent wars, and two decades of military and civilian research, damage-control resuscitation (DCR) is now widely used. This article will briefly describe the history of blood transfusion, outline "why we do DCR," and then discuss "how we do DCR." Modern DCR occurs both prehospital and in the hospital and has several main tenants. Currently, DCR focuses on the liberal use of temporary hemorrhage-control adjuncts, early use of whole blood or balanced blood product-based transfusions, mitigation of crystalloid use, hypotensive resuscitation to promote hemostasis and decrease coagulopathy, and correction of ongoing metabolic derangements, followed by rapid definitive hemorrhage control. These concepts have evolved from a series of lessons learned over time from both civilian and military trauma casualties, and DCR is now the standard of care in trauma resuscitation.
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