Prenatal diet, plasma micronutrients/metabolome and inflammatory status influence the development of atopic eczema in early childhood

AllergyAccepted Articles LETTER Prenatal Diet, Plasma Micronutrients/Metabolome And Inflammatory Status Influence The Development Of Atopic Eczema In Early Childhood Le Duc Huy Ta, Le Duc Huy Ta orcid.org/0000-0001-8579-0125 Department of Paediatrics, Yong Loo Lin School of Medicine, National University of SingaporeSearch for more papers by this authorJames Chun Yip Chan, James Chun Yip Chan Singapore Institute of Food and Biotechnology Innovation, A*STAR A*STAR Skin Research Labs, A*STARSearch for more papers by this authorGaik Chin Yap, Gaik Chin Yap Department of Paediatrics, Yong Loo Lin School of Medicine, National University of SingaporeSearch for more papers by this authorChiung-Hui Huang, Chiung-Hui Huang Department of Paediatrics, Yong Loo Lin School of Medicine, National University of SingaporeSearch for more papers by this authorElizabeth Huiwen Tham, Elizabeth Huiwen Tham orcid.org/0000-0003-1037-6143 Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore Khoo Teck Puat-National University Children's Medical Institute, National University Health System, SingaporeSearch for more papers by this authorEvelyn Xiu Ling Loo, Evelyn Xiu Ling Loo Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, SingaporeSearch for more papers by this authorNoor H. A. Suaini, Noor H. A. Suaini orcid.org/0000-0003-1161-8845 Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, SingaporeSearch for more papers by this authorLynette P. C. Shek, Lynette P. C. Shek Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, SingaporeSearch for more papers by this authorNeerja Karnani, Neerja Karnani Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, SingaporeSearch for more papers by this authorAnne Goh, Anne Goh Department of Paediatrics, KK Women's and Children's Hospital, SingaporeSearch for more papers by this authorHugo P. S. Van Bever, Hugo P. S. Van Bever Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore Khoo Teck Puat-National University Children's Medical Institute, National University Health System, SingaporeSearch for more papers by this authorOon Hoe Teoh, Oon Hoe Teoh Department of Paediatrics, KK Women's and Children's Hospital, SingaporeSearch for more papers by this authorYiong Huak Chan, Yiong Huak Chan Biostatistics Unit, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeSearch for more papers by this authorChristophe Lay, Christophe Lay Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore Danone Nutricia Research, SingaporeSearch for more papers by this authorJan Knol, Jan Knol Danone Nutricia Research, Utrecht, The Netherlands Wageningen University, Wageningen, The NetherlandsSearch for more papers by this authorFabian Yap, Fabian Yap Department of Paediatrics, KK Women's and Children's Hospital, SingaporeSearch for more papers by this authorKok Hian Tan, Kok Hian Tan Department of Paediatrics, KK Women's and Children's Hospital, SingaporeSearch for more papers by this authorYap-Seng Chong, Yap-Seng Chong Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore Department of Obstetrics & Gynaecology, National University of Singapore, SingaporeSearch for more papers by this authorMary Foong- Fong Chong, Mary Foong- Fong Chong Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, SingaporeSearch for more papers by this authorShiao Yng Chan, Shiao Yng Chan Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore Department of Obstetrics & Gynaecology, National University of Singapore, SingaporeSearch for more papers by this authorJohan Gunnar Eriksson, Johan Gunnar Eriksson Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore Department of Obstetrics & Gynaecology, National University of Singapore, Singapore Folkhälsan Research Center, Helsinki, Finland and Department of General Practice and Primary Health Care, University of Helsinki, Finland Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, FinlandSearch for more papers by this authorKeith M. Godfrey, Keith M. Godfrey MRC Lifecourse Epidemiology Centre and NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UKSearch for more papers by this authorEric Chun Yong Chan, Corresponding Author Eric Chun Yong Chan eric.chan@nus.edu.sg Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore Correspondence Bee Wah LEE. MD, FAAAAI, and Eric Chun Yong CHAN, PhD, MD1 - Tahir Foundation Building (MD1), Level 15, Department of Paediatrics, Allergy & Immunology Division, National University of Singapore (NUS), 12 Science Drive 2. Singapore 117549. Email: paeleebw@nus.edu.sg and eric.chan@nus.edu.sgSearch for more papers by this authorBee Wah Lee, Corresponding Author Bee Wah Lee paeleebw@nus.edu.sg Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore Correspondence Bee Wah LEE. MD, FAAAAI, and Eric Chun Yong CHAN, PhD, MD1 - Tahir Foundation Building (MD1), Level 15, Department of Paediatrics, Allergy & Immunology Division, National University of Singapore (NUS), 12 Science Drive 2. Singapore 117549. Email: paeleebw@nus.edu.sg and eric.chan@nus.edu.sgSearch for more papers by this author Le Duc Huy Ta, Le Duc Huy Ta orcid.org/0000-0001-8579-0125 Department of Paediatrics, Yong Loo Lin School of Medicine, National University of SingaporeSearch for more papers by this authorJames Chun Yip Chan, James Chun Yip Chan Singapore Institute of Food and Biotechnology Innovation, A*STAR A*STAR Skin Research Labs, A*STARSearch for more papers by this authorGaik Chin Yap, Gaik Chin Yap Department of Paediatrics, Yong Loo Lin School of Medicine, National University of SingaporeSearch for more papers by this authorChiung-Hui Huang, Chiung-Hui Huang Department of Paediatrics, Yong Loo Lin School of Medicine, National University of SingaporeSearch for more papers by this authorElizabeth Huiwen Tham, Elizabeth Huiwen Tham orcid.org/0000-0003-1037-6143 Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore Khoo Teck Puat-National University Children's Medical Institute, National University Health System, SingaporeSearch for more papers by this authorEvelyn Xiu Ling Loo, Evelyn Xiu Ling Loo Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, SingaporeSearch for more papers by this authorNoor H. A. Suaini, Noor H. A. Suaini orcid.org/0000-0003-1161-8845 Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, SingaporeSearch for more papers by this authorLynette P. C. Shek, Lynette P. C. Shek Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, SingaporeSearch for more papers by this authorNeerja Karnani, Neerja Karnani Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, SingaporeSearch for more papers by this authorAnne Goh, Anne Goh Department of Paediatrics, KK Women's and Children's Hospital, SingaporeSearch for more papers by this authorHugo P. S. Van Bever, Hugo P. S. Van Bever Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore Khoo Teck Puat-National University Children's Medical Institute, National University Health System, SingaporeSearch for more papers by this authorOon Hoe Teoh, Oon Hoe Teoh Department of Paediatrics, KK Women's and Children's Hospital, SingaporeSearch for more papers by this authorYiong Huak Chan, Yiong Huak Chan Biostatistics Unit, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeSearch for more papers by this authorChristophe Lay, Christophe Lay Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore Danone Nutricia Research, SingaporeSearch for more papers by this authorJan Knol, Jan Knol Danone Nutricia Research, Utrecht, The Netherlands Wageningen University, Wageningen, The NetherlandsSearch for more papers by this authorFabian Yap, Fabian Yap Department of Paediatrics, KK Women's and Children's Hospital, SingaporeSearch for more papers by this authorKok Hian Tan, Kok Hian Tan Department of Paediatrics, KK Women's and Children's Hospital, SingaporeSearch for more papers by this authorYap-Seng Chong, Yap-Seng Chong Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore Department of Obstetrics & Gynaecology, National University of Singapore, SingaporeSearch for more papers by this authorMary Foong- Fong Chong, Mary Foong- Fong Chong Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, SingaporeSearch for more papers by this authorShiao Yng Chan, Shiao Yng Chan Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore Department of Obstetrics & Gynaecology, National University of Singapore, SingaporeSearch for more papers by this authorJohan Gunnar Eriksson, Johan Gunnar Eriksson Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore Department of Obstetrics & Gynaecology, National University of Singapore, Singapore Folkhälsan Research Center, Helsinki, Finland and Department of General Practice and Primary Health Care, University of Helsinki, Finland Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, FinlandSearch for more papers by this authorKeith M. Godfrey, Keith M. Godfrey MRC Lifecourse Epidemiology Centre and NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UKSearch for more papers by this authorEric Chun Yong Chan, Corresponding Author Eric Chun Yong Chan eric.chan@nus.edu.sg Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore Correspondence Bee Wah LEE. MD, FAAAAI, and Eric Chun Yong CHAN, PhD, MD1 - Tahir Foundation Building (MD1), Level 15, Department of Paediatrics, Allergy & Immunology Division, National University of Singapore (NUS), 12 Science Drive 2. Singapore 117549. Email: paeleebw@nus.edu.sg and eric.chan@nus.edu.sgSearch for more papers by this authorBee Wah Lee, Corresponding Author Bee Wah Lee paeleebw@nus.edu.sg Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore Correspondence Bee Wah LEE. MD, FAAAAI, and Eric Chun Yong CHAN, PhD, MD1 - Tahir Foundation Building (MD1), Level 15, Department of Paediatrics, Allergy & Immunology Division, National University of Singapore (NUS), 12 Science Drive 2. Singapore 117549. Email: paeleebw@nus.edu.sg and eric.chan@nus.edu.sgSearch for more papers by this author First published: 02 November 2022 https://doi.org/10.1111/all.15573 This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. 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