Photoinduced Deaminative Alkylation of Quinoxalin‐2(1H)‐ones via an Electron Donor‐Acceptor Complex

Abstract Formation of C−C bonds by cleavage of the C(sp 3 )−N bonds of readily available alkyl amines is a valuable transformation. Herein, we report a method for oxidant‐ and metal‐free photoinduced deaminative alkylation of quinoxalin‐2(1 H )‐ones with Katritzky salts as alkyl radical sources. Various alkyl radicals could easily be generated by single‐electron reduction of electron donor–acceptor complexes between the Katritzky salts and sodium acetate. This green, sustainable, operationally simple method has a broad substrate scope, and can be used for gram‐scale synthesis, and late‐stage modification of pharmaceutically relevant molecules.