Synthesis of Spiro[4.5]ecanes by Au(I)‐Catalyzed Vinylogous Conia Ene Reaction

Abstract Au(I) catalysed vinylogous Conia ene reaction was developed to construct the densely functionalized spiro[4.5]‐deca‐1,6‐diene‐8‐ones from easily available 4‐alkyne tethered cyclohex‐2‐enones. 17 substrates with multiple substitutes on the cyclohex‐2‐enone ring were explored to afford the corresponding spiro[4.5]in 52–81 % yields. This reaction features mild conditions, wide substrate scope and atom economic characters.