Aversive memories can be weakened during human sleep via the reactivation of positive interfering memories

睡眠(系统调用) 心理学 神经科学 沟通 认知心理学 计算机科学 操作系统
作者
Tao Xia,Danni Chen,Shengzi Zeng,Ziqing Yao,Jing Liu,Shaozheng Qin,Ken A. Paller,Susana G. Torres‐Platas,James W. Antony,Xiaoqing Hu
标识
DOI:10.1101/2023.12.05.570072
摘要

Abstract Recollecting painful or traumatic experiences can be deeply troubling. Sleep may offer an opportunity to reduce such suffering. We developed a procedure to weaken older aversive memories by reactivating newer positive memories during sleep. Participants viewed 48 nonsense words each paired with a unique aversive image, followed by an overnight sleep. In the next evening, participants learned associations between half of the words and additional positive images, creating interference. During the following non-rapid-eye-movement sleep, auditory memory cues were unobtrusively delivered. Upon waking, presenting cues associated with both aversive and positive images during sleep, as opposed to not presenting cues, weakened aversive memory recall while increasing positive memory intrusions. Substantiating these memory benefits, computational modeling revealed that cueing facilitated evidence accumulation toward positive affect judgments. Moreover, cue-elicited theta brain rhythms during sleep predominantly predicted the recall of positive memories. A noninvasive sleep intervention can thus modify aversive recollection and affective responses. Significance Statement Not all memories are welcome: recollection and involuntary intrusions of aversive memories can be debilitating. Prior research shows that reactivating positive memories benefits psychological health, and memory reactivation can be externally triggered during human sleep. Here, we introduced a novel sleep-based memory updating procedure to weaken older aversive memories by reactivating newer positive memories. We found that such reactivation not only weakened the recall of aversive memories, but also increased involuntary intrusion of positive memories. Moreover, reactivation enhanced positive affect judgments. Our findings open new avenues for weakening aversive or traumatic memories during human sleep.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
李爱国应助科研通管家采纳,获得10
3秒前
科研通AI2S应助科研通管家采纳,获得10
3秒前
搜集达人应助科研通管家采纳,获得10
3秒前
打地鼠工人完成签到,获得积分10
4秒前
彩色半烟完成签到,获得积分10
6秒前
量子星尘发布了新的文献求助10
10秒前
Ning完成签到,获得积分10
13秒前
图图完成签到,获得积分10
13秒前
勤奋的灯完成签到 ,获得积分10
13秒前
ludong_0完成签到,获得积分10
13秒前
Asumita完成签到,获得积分10
14秒前
双青豆完成签到 ,获得积分10
14秒前
16秒前
fxy完成签到 ,获得积分10
17秒前
合适的幻然完成签到,获得积分10
17秒前
沐雨汐完成签到,获得积分10
19秒前
21秒前
22秒前
jiayoujijin完成签到 ,获得积分10
22秒前
淡然思卉完成签到,获得积分10
23秒前
争当科研巨匠完成签到,获得积分10
23秒前
英姑应助认真的刺猬采纳,获得10
30秒前
好大一只小坏蛋完成签到,获得积分20
30秒前
站走跑完成签到 ,获得积分10
33秒前
步步高完成签到,获得积分10
35秒前
无私的雪瑶完成签到 ,获得积分10
35秒前
小杨完成签到,获得积分20
36秒前
小花完成签到 ,获得积分10
41秒前
宁夕完成签到 ,获得积分10
45秒前
西宁完成签到,获得积分10
45秒前
拼搏的羊青完成签到 ,获得积分10
46秒前
科目三应助asd113采纳,获得10
46秒前
deng203完成签到 ,获得积分20
48秒前
49秒前
时米米米完成签到,获得积分10
49秒前
浅浅完成签到,获得积分10
53秒前
量子星尘发布了新的文献求助10
58秒前
帅气的藏鸟完成签到,获得积分10
1分钟前
加油完成签到 ,获得积分10
1分钟前
健康的宛菡完成签到 ,获得积分10
1分钟前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds.Vol2 1100
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038066
求助须知:如何正确求助?哪些是违规求助? 3575779
关于积分的说明 11373801
捐赠科研通 3305584
什么是DOI,文献DOI怎么找? 1819239
邀请新用户注册赠送积分活动 892655
科研通“疑难数据库(出版商)”最低求助积分说明 815022