医学
微卫星不稳定性
彭布罗利珠单抗
肿瘤微环境
无容量
免疫疗法
肿瘤科
胰腺癌
免疫检查点
癌症
临床试验
PD-L1
内科学
癌症研究
生物化学
等位基因
化学
微卫星
基因
作者
Himil Mahadevia,Pedro Luiz Serrano Usón,Jing Wang,Mitesh J. Borad,Hani M. Babiker
标识
DOI：10.1080/14656566.2024.2304125
摘要
Introduction Immune checkpoint inhibitors (ICIs) targeting programmed cell death protein-1 (PD-1/PD-L1) pathway as well as cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) have demonstrated substantial potential in several malignancies. Pancreatic adenocarcinoma (PC) still carries a high mortality despite tremendous advances in the anti-cancer arsenal.
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