Acute coronary syndrome and stress: Is there a relationship?

医学 急性冠脉综合征 内科学 心肌梗塞 人口 心脏病学 病理生理学 环境卫生
作者
H Santos,Mariana Santos,Sofia B. Paula,Margarida Figueiredo,Inês Almeida,Hugo Miranda,Joana Chin,Catarina Sá,Micaela Neto,Samuel Almeida,Catarina Sousa,Lurdes Almeida
出处
期刊:Revista portuguesa de cardiologia [Elsevier]
卷期号:42 (1): 9-17 被引量:3
标识
DOI:10.1016/j.repc.2021.09.016
摘要

Acute coronary syndrome (ACS) is the result of a complex pathophysiological process with various dynamic factors. The 10-item Perceived Stress Scale (PSS-10) is a validated instrument for estimating stress levels in clinical practice and may be useful in the assessment of ACS. We carried out a single-center prospective study engaging patients hospitalized with ACS between March 20, 2019 and March 3, 2020. The PSS-10 was completed during the hospitalization period. The ACS group was compared to a control group (the general Portuguese population), and a subanalysis in the stress group were then performed. A total of 171 patients with ACS were included, of whom 36.5% presented ST-elevation myocardial infarction (STEMI), 38.1% were female and the mean PSS score was 19.5 ± 7.1. Females in the control group scored 16.6 ± 6.3 on the PSS-10 and control males scored 13.4 ± 6.5. The female population with ACS scored 22.8 ± 9.8 on the PSS-10 (p<0.001). Similarly, ACS males scored a mean of 17.4 ± 6.4 (p<0.001). Pathological stress levels were not a predictor of major adverse cardiovascular events or severity at admission. ACS patients had higher perceived stress levels compared to the control group. Perceived stress level was not associated with worse prognosis in ACS patients. Síndrome coronária aguda (SCA) é resultado de uma complexa relação entre fatores dinâmico-indivíduais e processos fiso-patologicos inerentes a cada indivíduo. A Perceived Stress Scale (PSS-10) é um instrumento válido e usado habitualmente na prática clínica e pode ser usado na avaliação do stress percecionado em doentes com SCA. Estudo prospetivo que incluiu doentes hospitalizados por SCA entre 20/03/2019-31/03/2020. PSS-10 foi realizado durante o internamento por SCA. O grupo de doentes com SCA foi comparado com a população controlo (população portuguesa geral) e posteriormente a subanálise do grupo SCA foi executada. Foram incluídos 171 doentes com SCA, 36,5% apresentaram Enfarte Agudo do Miocárdio com Elevação do Segmento ST (EAMCESST), 38,1% eram mulheres com uma pontuação média no PSS-10 de 19,5 ± 7,1. As mulheres na população controlo têm em média 16,6 ± 6,3 pontos na PSS-10, enquanto a população masculina controlo tem 13,4 ± 6,5 pontos. As mulheres no grupo com SCA apresentaram 22,8 ± 9,8 pontos na PSS-10 (p<0,001). Por sua vez, o género masculino com SCA apresentou 17,4 ± 6,4 pontos na PSS-10, p<0,001. Níveis patológicos de stress percecionado não foram preditores de eventos cardiovasculares major nem de gravidade na admissão. Os doentes com SCA apresentaram maiores índices de stress percecionado comparando com a população controlo. Maiores níveis de stress percecionado não foram associados a pior prognóstico em doentes com SCA.
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