化学
乙腈
色谱法
重复性
萃取(化学)
质谱法
串联质谱法
分析物
线性范围
检出限
墨盒
串联
机械工程
工程类
复合材料
材料科学
作者
Yan Yan,Shuang Zhang,Guanjun Tao,You Feng-hui,Jie Chen,Maomao Zeng
标识
DOI:10.1016/j.jchromb.2017.10.015
摘要
This study proposed a simple and accurate acetonitrile extraction pretreatment method coupled with ultrahigh-performance liquid chromatography with tandem mass spectrometry for the simultaneous determination of 17 heterocyclic aromatic amines (HAAs) in meat products. With this new method, all 17 HAAs, including 11 polar and 6 nonpolarHAAs, were simultaneously extracted by acetonitrile and purified by one-step Oasis MCX cartridge purification. Compared with two different improved reference methods, the acetonitrile method could obtain higher recoveries (in the range of 42.5% to 99.0%) and better repeatability (lower than 12.2%). The limits of quantification were calculated between 0.028ngg-1and0.648ngg-1 with high correlation coefficients (r>0.9976) in wide linear ranges. The proposed acetonitrile method was successfully applied to the analysis of the HAAs levels in 10 commercial meat products with satisfactory recoveries.
科研通智能强力驱动
Strongly Powered by AbleSci AI