FGF19型
酒精性肝炎
酒精性肝病
胆汁酸
内科学
胆汁淤积
胃肠病学
医学
肝炎
肝病
自身免疫性肝炎
肝硬化
成纤维细胞生长因子
受体
作者
Katharina Brandl,Phillipp Hartmann,Lily Jih,Donald Pizzo,Josepmaria Argemí,Meritxell Ventura‐Cots,Sally Coulter,Christopher Liddle,Lei Ling,Stephen J. Rossi,Alex M. DePaoli,Rohit Loomba,Wajahat Z. Mehal,Derrick E. Fouts,Michael R. Lucey,Francisco Bosques‐Padilla,Philippe Mathurin,Alexandre Louvet,Guadalupe García–Tsao,Elizabeth C. Verna
标识
DOI:10.1016/j.jhep.2018.03.031
摘要
Understanding the underlying mechanisms that drive alcoholic hepatitis is important for the development of new biomarkers and targeted therapies. Herein, we describe a molecule that is increased in patients with alcoholic hepatitis. Modulating the molecular pathway of this molecule might lead to promising targets for the treatment of alcoholic hepatitis.
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