Hybrid procedure combining endoscopic gallbladder lavage and internal drainage with elective cholecystectomy for acute cholecystitis: A prospective pilot study (The BLADE study)

医学 胆囊 外科 胆囊炎 经皮 急性胆囊炎 不利影响 支架 穿孔 胆囊切除术 胰腺炎 前瞻性队列研究 普通外科 内科学 材料科学 冶金 冲孔
作者
Shinpei Doi,Ichiro Yasuda,Masatoshi Mabuchi,Keisuke Iwata,Nobuhiro Ando,Takuji Iwashita,Shinya Uemura,Mitsuru Okuno,Tsuyoshi Mukai,Seiji Adachi,Koki Taniguchi
出处
期刊:Digestive Endoscopy [Wiley]
卷期号:30 (4): 501-507 被引量:22
标识
DOI:10.1111/den.13028
摘要

Background and Aim Percutaneous transhepatic drainage is the most common method for non‐operative gallbladder drainage, but the technique does have several disadvantages because of its invasive nature and requirement for continuous drainage. To overcome these disadvantages, we developed a novel procedure, endoscopic gallbladder lavage followed by stent placement, carried out in a single endoscopic session. Our aim was to prospectively evaluate the efficacy and safety of this procedure in patients with acute cholecystitis. Methods Patients diagnosed with moderate cholecystitis at four tertiary care centers were enrolled in this study. We initially placed a 5‐Fr tube to carry out gallbladder lavage. The tube was then cut to the optimal length and placed as a stent. Main outcomes were procedural and clinical success rates. Results The procedure was attempted in 40 patients and was successful in 30 (75.0%). Minor adverse events occurred in two (5.0%) patients: perforation of the cystic duct by the guidewire in one patient and pancreatitis in the other. Among the 30 patients in whom the procedure was successfully done, clinical resolution was obtained in 29 (96.6%). Elective cholecystectomy was carried out in 37 patients (92.5%), with a median delay after drainage of 42 days (range, 12–138 days). There were no adverse events during the waiting period. Conclusions Gallbladder rinsing followed by internal drainage using a 5‐Fr nasobiliary tube is considered an effective and safe alternative to other techniques, providing an acceptable success rate in patients with acute cholecystitis prior to elective surgery. Clinical trial information: http://www.umin.ac.jp/ctr/index.htm (ID: UMIN‐000009680).
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
1秒前
妮露的修狗完成签到,获得积分10
1秒前
经济完成签到,获得积分10
1秒前
2秒前
Hello应助科研通管家采纳,获得10
2秒前
深情安青应助科研通管家采纳,获得10
2秒前
calendar应助科研通管家采纳,获得10
2秒前
烟花应助科研通管家采纳,获得10
2秒前
2秒前
2秒前
田様应助科研通管家采纳,获得10
2秒前
Hello应助科研通管家采纳,获得10
2秒前
CipherSage应助科研通管家采纳,获得10
2秒前
3秒前
彭于晏应助科研通管家采纳,获得10
3秒前
完美世界应助科研通管家采纳,获得10
3秒前
研友_VZG7GZ应助科研通管家采纳,获得10
3秒前
脑洞疼应助科研通管家采纳,获得10
3秒前
3秒前
Owen应助科研通管家采纳,获得10
3秒前
FashionBoy应助科研通管家采纳,获得10
3秒前
3秒前
3秒前
3秒前
3秒前
五虎完成签到,获得积分10
3秒前
传奇3应助XYWang采纳,获得30
4秒前
香蕉觅云应助小九采纳,获得10
4秒前
在水一方应助谦让的含海采纳,获得10
4秒前
5秒前
山河入怀发布了新的文献求助10
5秒前
seaya完成签到,获得积分10
6秒前
李爱国应助舒服的盼秋采纳,获得10
7秒前
妮妮完成签到,获得积分10
7秒前
7秒前
坚定不移完成签到,获得积分10
8秒前
克己复礼应助guoyanna采纳,获得10
8秒前
Hello应助Seven采纳,获得10
8秒前
玲儿发布了新的文献求助10
8秒前
高分求助中
Sustainability in Tides Chemistry 2000
The ACS Guide to Scholarly Communication 2000
Studien zur Ideengeschichte der Gesetzgebung 1000
TM 5-855-1(Fundamentals of protective design for conventional weapons) 1000
Threaded Harmony: A Sustainable Approach to Fashion 810
Pharmacogenomics: Applications to Patient Care, Third Edition 800
A Dissection Guide & Atlas to the Rabbit 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3078480
求助须知:如何正确求助?哪些是违规求助? 2731193
关于积分的说明 7517547
捐赠科研通 2379617
什么是DOI,文献DOI怎么找? 1261779
科研通“疑难数据库(出版商)”最低求助积分说明 611752
版权声明 597350