医学
癫痫
临床实习
药品
临床疗效
重症监护医学
精神科
内科学
物理疗法
作者
Guoxing Zhu,Xunyi Wu,Peimin Yu,Jinyang Wang,Yue Zhang,Zhen Hong
出处
期刊:Chin J Neurol
日期:2011-01-08
卷期号:44 (01): 6-9
被引量:1
标识
DOI:10.3760/cma.j.issn.1006-7876.2011.01.004
摘要
Objective To formulate and detect the efficacy and safety of standardized medication strategy of epilepsy. Methods The normalized medication strategy was worked out in 278 new diagnosed patients, whose effect, retention rate and safety were evaluated after 24 months of treatment. Results Of all the 278 patients, 235 patients were taken mono-therapy while other 43 patients used therapeutic alliance.Most patients took CBZ or VPA as mono-therapy drugs. At the time after 24 months, almost 76. 3%(212/278) patients got seizure free, and the effectiveness was 22. 7% (63/278). The retention rate of those mono-therapy drugs were investigated respectively. CBZ presented 69. 8%, VPA presented 76. 2%,OXC was 68.0%, TPM was 69. 6%, LTG was 83. 3%, LEV presented 85.7%, and 100% for PHT.Conclusions All epileptic patients were well-controlled after taking standardized medication. The standardized medication strategy of epilepsy possesses valuable importance in clinical practice, which deserves further popularization.
Key words:
Epilepsy; Drug therapy; Clinical protocols
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