医学
胰十二指肠切除术
胃排空
胰瘘
随机对照试验
批判性评价
奇纳
营养补充
营养不良
科克伦图书馆
外科
普通外科
内科学
胰腺
替代医学
胃
病理
精神科
心理干预
作者
Jordyn Dangen,Kylie Porritt,Saleh Abbas
出处
期刊:JBI evidence synthesis
[Joanna Briggs Institute]
日期:2020-12-31
卷期号:Publish Ahead of Print
标识
DOI:10.11124/jbies-20-00227
摘要
Objective: This review aims to present the best available evidence related to the effect of preoperative nutritional supplementation on postoperative outcomes for patients undergoing pancreaticoduodenectomy for cancer. Introduction: Pancreaticoduodenectomy surgery is the only curative option for early head of pancreas and periampullary cancers. This complex, high-risk procedure is associated with significant morbidity, making opportunities to improve outcomes paramount. Nutritional supplementation in the preoperative period may enhance the body's ability to withstand the stress of major surgery and reduce postoperative complications. Inclusion criteria: This review will consider studies of patients undergoing pancreaticoduodenectomy for cancer who are provided preoperative nutritional supplementation in any form for a minimum of 48 hours. Randomized and quasi-randomized trials that compare any form of preoperative nutritional supplementation to standard care in these patients will be included. Outcome data will include hospital length of stay, mortality, infections, delayed gastric emptying, pancreatic fistula, anastomotic leak, hemorrhage, weight loss, body mass index, serum albumin, lymphocyte levels, and nutrition risk index score. Methods: Electronic databases (PubMed, Scopus, CINAHL, and Cochrane Library) and trial registers will be searched for published and unpublished articles. All articles from database inception to present, published in any language will be included. One reviewer will perform the literature search, screen texts for inclusion, and extract data. Two authors will assess methodological quality of the literature using the JBI critical appraisal tool. Authors will be contacted where additional data or clarification is required. Statistical meta-analysis through synthesis and pooling of data for each intervention will be completed where meaningful. Systematic review registration number: PROSPERO CRD42020215307
科研通智能强力驱动
Strongly Powered by AbleSci AI