光催化
DNA损伤
活性氧
纳米技术
光电子学
材料科学
DNA
化学
生物化学
催化作用
作者
Wenbo Li,Cheng Wang,Yingfang Yao,Congping Wu,Wenjun Luo,Zhigang Zou
标识
DOI:10.1016/j.trechm.2020.10.002
摘要
Photo-therapeutics have attracted increasing attention for the treatment of tumors because of their controllable and tunable nature and low potential for side effects. Photocatalytic materials triggered by targeted wavelengths of light facilitate the generation of reactive oxygen species for tumor DNA damage, allowing for high efficacy at low radiation doses with limited damage of normal tissues. This short review emphasizes the mechanisms and recent breakthroughs achieved in photocatalytic materials for tumor treatment, mainly focusing on light wavelengths in the respective near-infrared (NIR), UV-vis, and X-ray regions. Lastly, current limitations and future perspectives are also highlighted.
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