16359 Evaluation of efficacy of a serum containing five types of hyaluronic acid with different molecular weights in increasing production of collagen type I in the dermis

Introduction and Objective: With aging, the genetic material of the skin changes due to a significant reduction in synthesis enzymes. As a result, epithelial tissue loses elasticity and lift, replication becomes less efficient and wrinkles appear. Hyaluronic acid (HA) is one of the main components of the extracellular matrix, essential for skin hydration, density, firmness and filling. The aim of the present study was to evaluate the efficacy a serum containing five types of HA with different molecular weights in increasing production of collagen type I in the dermis.