真皮
透明质酸
细胞外基质
医学
Ⅰ型胶原
分子质量
生物化学
酶
解剖
病理
化学
作者
Jayme Filho,Giselle Canavaci,Louise de Matos
标识
DOI:10.1016/j.jaad.2020.06.795
摘要
Introduction and Objective: With aging, the genetic material of the skin changes due to a significant reduction in synthesis enzymes. As a result, epithelial tissue loses elasticity and lift, replication becomes less efficient and wrinkles appear. Hyaluronic acid (HA) is one of the main components of the extracellular matrix, essential for skin hydration, density, firmness and filling. The aim of the present study was to evaluate the efficacy a serum containing five types of HA with different molecular weights in increasing production of collagen type I in the dermis.
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