生物
全基因组关联研究
遗传学
单核苷酸多态性
计算生物学
数量性状位点
基因
基因型
作者
Mei Li,Yawen Zhang,Yu‐Tao Xiang,M. Liu,Yuan‐Ming Zhang
出处
期刊:Molecular Plant
[Elsevier]
日期:2022-08-01
卷期号:15 (8): 1251-1253
被引量:43
标识
DOI:10.1016/j.molp.2022.06.002
摘要
In most existing methods and softwares of genome-wide association studies (GWAS) for detecting quantitative trait nucleotides (QTNs), QTN-by-environment interactions (QEIs), and QTN-by-QTN interactions (QQIs), only the allele substitution effect and its interaction-related effects are detected and estimated, conditional on method-specific polygenic background control, leading to confounding in effect estimation and insufficient polygenic background control (Li et al., 2022; Supplemental Tables 1‒3).
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