SARCOPENIC OBESITY IN PATIENTS RECEIVING TREATMENT WITH PROGRAMMED HEMODIALYSIS

肌萎缩性肥胖 医学 血液透析 肾脏替代疗法 肥胖 内科学 肾脏疾病 流行病学 肌酐 透析 病态的
作者
A. Sh. Rumyantsev,P. Yu. Filinyuk,A. A. Jakovenko,M. H. Khasun,N. Yu. Korosteleva,I. Yu. Panina,N. N. Kulaeva
出处
期刊:Нефрология [Non-profit organization Nephrology]
卷期号:26 (2): 77-84 被引量:2
标识
DOI:10.36485/1561-6274-2022-26-2-77-84
摘要

BACKGROUND . The term "sarcopenic obesity" has been used not so long ago. The epidemiology of this phenomenon during renal replacement therapy in the Russian Federation has not been studied. THE AIM : to assess the prevalence of sarcopenic obesity in patients on hemodialysis (HD). PATIENTS AND METHODS . 140 patients receiving treatment with programmed bicarbonate HD in 2 dialysis centers of St. Petersburg were examined, among them 68 women and 72 men, the average age was 56.8±12.8 years. The main cause of the development of terminal renal insufficiency was chronic glomerulonephritis – in 43, autosomal dominant polycystic kidney disease – in 14, chronic pyelonephritis – in 9, hypertension – in 15, chronic tubulointerstitial nephritis – in 6 and other diseases – in 53 people. The prevalence of these pathological conditions in men and women did not differ. To assess the component composition of the patient's body, we used: 8–point tactile tetrapolar multi–frequency bioimpedance (BIM) on the InBody device (South Korea) with a frequency range of 1 – 1000 kHz, 10 measurements for each of 6 frequencies for each of 5 body segments (right and left arm, right and left leg, torso), followed by the calculation of the index of appendicular skeletal muscles. The criteria of RN. Baumgartner (2000) were used to diagnose sarcopenic obesity. RESULTS . Sarcopenic obesity was detected in 62 patients (44.3 %). There was no correlation with the underlying pathology. Patients with sarcopenic obesity were distinguished by a longer period of renal replacement therapy, the lowest concentration of serum creatinine and the number of points of the physical component of the SF-36 scale, higher levels of C-reactive protein, parathyroid hormone, HOMA-IR index, Charleson index. Also in this group, the lowest score on the IPAQ scale of motor activity and the worst results in the 6-minute walking test were noted. CONCLUSION . Currently, it is not entirely clear what is the primary link in the development of sarcopenic obesity and whether it is realistic to isolate it in a particular patient. We believe that the main cause of the development of this syndrome is obesity, which causes the expression of pro-inflammatory cytokines and insulin resistance. The most important modifiable risk factor for obesity is considered to be the hypercaloric intake of patients, which is due to the lack of nutritionists with experience in the field of nephrology and indexing the amount of calories indicated in clinical recommendations to the real, and not to the recommended body weight.

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
钟离的狗完成签到 ,获得积分10
1秒前
Ava应助快乐的凡霜采纳,获得10
1秒前
2秒前
jimmy完成签到,获得积分10
3秒前
乐乐完成签到,获得积分10
3秒前
zzz发布了新的文献求助10
3秒前
3秒前
科研通AI5应助孙友浩采纳,获得10
4秒前
4秒前
677完成签到,获得积分10
5秒前
5秒前
上官若男应助Tseeee采纳,获得10
5秒前
5秒前
小王完成签到,获得积分10
5秒前
5秒前
5秒前
佚名完成签到,获得积分10
5秒前
难过机器猫完成签到,获得积分10
6秒前
尕青年发布了新的文献求助10
6秒前
zong完成签到,获得积分10
6秒前
Zn应助1+1采纳,获得10
7秒前
CipherSage应助马骥采纳,获得10
7秒前
YUUNEEQUE完成签到,获得积分10
8秒前
ddz发布了新的文献求助10
8秒前
9秒前
wang666发布了新的文献求助10
9秒前
慕青应助三度和弦采纳,获得10
9秒前
帝蒼完成签到,获得积分10
10秒前
我在家里睡觉就不会被打扰了完成签到,获得积分20
10秒前
10秒前
甜蜜英姑发布了新的文献求助10
10秒前
咿呀应助JJ采纳,获得40
10秒前
YORLAN发布了新的文献求助10
11秒前
燕子完成签到,获得积分10
11秒前
科研通AI5应助wsg采纳,获得10
13秒前
13秒前
MIA903完成签到,获得积分10
13秒前
竹子完成签到,获得积分10
14秒前
风趣的之桃完成签到 ,获得积分10
14秒前
14秒前
高分求助中
Continuum Thermodynamics and Material Modelling 3000
Production Logging: Theoretical and Interpretive Elements 2700
Kelsen’s Legacy: Legal Normativity, International Law and Democracy 1000
Conference Record, IAS Annual Meeting 1977 610
The Laschia-complex (Basidiomycetes) 600
Interest Rate Modeling. Volume 3: Products and Risk Management 600
Interest Rate Modeling. Volume 2: Term Structure Models 600
热门求助领域 (近24小时)
化学 材料科学 生物 医学 工程类 有机化学 生物化学 物理 纳米技术 计算机科学 内科学 化学工程 复合材料 基因 遗传学 物理化学 催化作用 量子力学 光电子学 冶金
热门帖子
关注 科研通微信公众号,转发送积分 3540304
求助须知:如何正确求助?哪些是违规求助? 3117769
关于积分的说明 9332287
捐赠科研通 2815471
什么是DOI,文献DOI怎么找? 1547621
邀请新用户注册赠送积分活动 721067
科研通“疑难数据库(出版商)”最低求助积分说明 712445