自愈水凝胶
生物相容性
羧甲基纤维素
环氧氯丙烷
药物输送
肿胀 的
材料科学
纤维素
药品
化学工程
纳米技术
化学
复合材料
高分子化学
有机化学
药理学
冶金
钠
工程类
医学
作者
Cătălina Anişoara Peptu,Elena Simona Băcăiţă,Corina-Lenuța Logigan,Marian Luţcanu,Maricel Agop
出处
期刊:Polymers
[MDPI AG]
日期:2021-12-20
卷期号:13 (24): 4461-4461
被引量:7
标识
DOI:10.3390/polym13244461
摘要
New hydrogels films crosslinked with epichlorohydrin were prepared based on alginates and carboxymethyl cellulose with properties that recommend them as potential drug delivery systems (e.g., biocompatibility, low toxicity, non-immunogenicity, hemostatic activity and the ability to absorb large amounts of water). The characterization of their structural, morphological, swelling capacity, loading/release and drug efficiency traits proved that these new hydrogels are promising materials for controlled drug delivery systems. Further, a new theoretical model, in the framework of Scale Relativity Theory, was built with to offer insights on the release process at the microscopic level and to simplify the analysis of the release process.
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