Social evolution of shared biofilm matrix components

生物膜 基质(化学分析) 生物系统 生物 霍乱弧菌 生化工程 生态学 进化生物学
作者
Jung-Shen B. Tai,Saikat Mukherjee,Thomas Nero,Rich Olson,Jeffrey Tithof,Carey D. Nadell,Jing Yan
标识
DOI:10.1101/2021.12.16.472970
摘要

Abstract Biofilm formation is an important and ubiquitous mode of growth among bacteria. Central to the evolutionary advantage of biofilm formation is cell-cell and cell-surface adhesion achieved by a variety of factors, some of which are diffusible compounds that may operate as classical public goods – factors that are costly to produce but may benefit other cells. An outstanding question is how diffusible matrix production, in general, can be stable over evolutionary timescales. In this work, using Vibrio cholerae as a model, we show that shared diffusible biofilm matrix proteins are indeed susceptible to cheater exploitation, and that the evolutionary stability of producing these matrix components fundamentally depends on biofilm spatial structure, intrinsic sharing mechanisms of these components, and flow conditions in the environment. We further show that exploitation of diffusible adhesion proteins is localized within a well-defined spatial range around cell clusters that produce them. Based on this exploitation range and the spatial distribution of cell clusters, we construct a model of costly diffusible matrix production and relate these length scales to the relatedness coefficient in social evolution theory. Our results show that production of diffusible biofilm matrix components is evolutionarily stable under conditions consistent with natural biofilm habitats and host environments. We expect the mechanisms revealed in this study to be relevant to other secreted factors that operate as cooperative public goods in bacterial communities, and the concept of exploitation range and the associated analysis tools to be generally applicable.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
LXP发布了新的文献求助10
刚刚
刚刚
1秒前
酷波er应助hei采纳,获得10
1秒前
火星完成签到 ,获得积分10
1秒前
2秒前
傻傻的小刺猬完成签到,获得积分10
2秒前
科研通AI2S应助陌路孤星采纳,获得10
3秒前
3秒前
4秒前
5秒前
5秒前
12123ray发布了新的文献求助10
5秒前
6秒前
moomoo完成签到 ,获得积分10
7秒前
zw发布了新的文献求助10
7秒前
Orange应助俏皮念寒采纳,获得10
7秒前
Donby发布了新的文献求助30
7秒前
7秒前
从容的从寒完成签到,获得积分10
9秒前
迅速采波发布了新的文献求助10
9秒前
黑苹果发布了新的文献求助10
10秒前
jiajia发布了新的文献求助10
10秒前
巡音幻夜发布了新的文献求助10
10秒前
嘉子发布了新的文献求助10
10秒前
11秒前
慕青应助彩色蘑菇采纳,获得10
11秒前
SHD发布了新的文献求助10
12秒前
KKKKK完成签到,获得积分10
12秒前
ylq发布了新的文献求助10
12秒前
12秒前
iNk应助LinX采纳,获得10
13秒前
qingzhiwu完成签到,获得积分10
14秒前
14秒前
今夜不设防发布了新的文献求助150
15秒前
15秒前
15秒前
赤江之木完成签到 ,获得积分10
17秒前
17秒前
高分求助中
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
Effective Learning and Mental Wellbeing 300
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3974882
求助须知:如何正确求助?哪些是违规求助? 3519431
关于积分的说明 11198315
捐赠科研通 3255698
什么是DOI,文献DOI怎么找? 1797904
邀请新用户注册赠送积分活动 877237
科研通“疑难数据库(出版商)”最低求助积分说明 806219