生物相容性
抗菌活性
细菌纤维素
材料科学
抗菌剂
螯合作用
原位聚合
抗菌剂
纳米材料
组合化学
纤维素
纳米技术
复合材料
化学
聚合
有机化学
聚合物
冶金
细菌
抗生素
生物
生物化学
遗传学
作者
Yajie Xie,Lina Yue,Yudong Zheng,Liang Zhao,Chunyong Liang,Wei He,Zhiwei Liu,Yi Sun,Yingying Yang
标识
DOI:10.1016/j.apsusc.2019.06.096
摘要
In recent years, continuous and stable antibacterial ability has received extensive attention in the field of antibacterial composite materials. The researchers expect a kind of antibacterial composites with continuous and stable antibacterial acting and good biocompatibility. Herein we used a unique in-situ modification methods which inspired self-polymerization of dopamine to fix the nano-Ag on the bacterial cellulose (BC). The antibacterial properties of composites were tested in two new methods (antibacterial stability and antibacterial durability). We researched the cause of the antibacterial properties by analyzing the valence state and binding energy of Ag. The chelation between PDA and Ag is considered to the key to stable release of Ag + . The three-dimensional network of BC is also thought to play some role in making Ag + release stability. Moreover, PDA as a reducing agent, reacting with Tollens reagent to produce nano-Ag nanoparticles, is a good method for reducing the toxicity of nano-Ag and enhancing the biological compatibility of composites. Our results hence illustrate that the BC antimicrobial composites by PDA in-situ reduction nano-Ag has a great potential as an antibacterial dressing with stable antimicrobial properties and biocompatibility. • PDA can reduce toxicity of nano-Ag and enhance biocompatibility of composites. • Antibacterial properties are tested in two methods called stability and durability. • The cause of antibacterial properties is researched by XPS and Ag + release curve.
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