蜱传疾病
滴答声
无浆体病
巴贝虫病
埃立克体病
斑点热
生物
莱姆病
立克次体病
复发性发热
嗜噬粒细胞间质
螺旋体
移行性红斑
疾病
免疫学
脑炎
蜱传脑炎
病毒学
医学
伯氏疏螺旋体
立克次体
内科学
病毒
抗体
莱姆病
作者
Hongbo Liu,Ran Wei,Xue-Bing Ni,Yuan-Chun Zheng,Qiu-Bo Huo,Bao-Gui Jiang,Lan Ma,Rui-Ruo Jiang,Jin Lv,Yunxi Liu,Fang Yang,Yun-Huan Zhang,Jia-Fu Jiang,Na Jia,Wu‐Chun Cao
出处
期刊:Parasitology
[Cambridge University Press]
日期:2018-08-01
卷期号:146 (2): 161-167
被引量:11
标识
DOI:10.1017/s0031182018001178
摘要
Abstract Northeastern China is a region of high tick abundance, multiple tick-borne pathogens and likely human infections. The spectrum of diseases caused by tick-borne pathogens has not been objectively evaluated in this region for clinical management and for comparison with other regions globally where tick-transmitted diseases are common. Based on clinical symptoms, PCR, indirect immunofluorescent assay and (or) blood smear, we identified and described tick-borne diseases from patients with recent tick bite seen at Mudanjiang Forestry Central Hospital. From May 2010 to September 2011, 42% (75/180) of patients were diagnosed with a specific tick-borne disease, including Lyme borreliosis, tick-borne encephalitis, human granulocytic anaplasmosis, human babesiosis and spotted fever group rickettsiosis. When we compared clinical and laboratory features to identify factors that might discriminate tick-transmitted infections from those lacking that evidence, we revealed that erythema migrans and neurological manifestations were statistically significantly differently presented between those with and without documented aetiologies ( P < 0.001, P = 0.003). Twelve patients (6.7%, 12/180) were co-infected with two tick-borne pathogens. We demonstrated the poor ability of clinicians to identify the specific tick-borne disease. In addition, it is necessary to develop specific laboratory assays for optimal diagnosis of tick-borne diseases.
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