医学
前列腺切除术
前列腺癌
雄激素剥夺疗法
多西紫杉醇
放射治疗
肿瘤科
随机对照试验
内科学
解剖(医学)
癌症
泌尿科
放射科
作者
Shingo Hatakeyama,Chikara Οhyama
出处
期刊:PubMed
日期:2016-01-01
卷期号:74 (1): 114-9
被引量:1
摘要
Multimodal approach should be provided for high-risk prostate cancer patients. Androgen deprivation therapy (ADT) is a standard adjunct to radiotherapy for high-risk prostate cancer, but its role around prostatectomy has not been clearly defined. In a well-selected patient group, radical prostatectomy with adjuvant or salvage treatment when needed can yield very high long-term cancer control and survival rates. The role of pelvic lymph node dissection during radical prostatectomy is still controversial. Recent randomized controlled trials have demonstrated improved outcomes with the combination of radiotherapy in conjunction with ADT and docetaxel for high-risk prostate cancer. Innovations to detect oligometastasis, and systemic chemotherapies combined with local therapy will open up new landscape for further improved outcomes in patients with high-risk prostate cancer.
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