乙醇钠
化学
甲胺
取代基
SN2反应
甲醇钠
亲核取代
桂皮酸盐类
邻苯二甲酰亚胺
氨解
药物化学
有机化学
甲醇
催化作用
邻苯二甲酰亚胺
乙醇
作者
Yasemin Soydaş Bozkurt,Halil Kütük
标识
DOI:10.1080/10426507.2011.561457
摘要
Abstract In this study, some N-(p-substituted-arylsulfinyl)phthalimides (1a–1e) were synthesized. The synthesized compounds were examined with respect to their substitution reactions with sodium ethoxide, sodium methoxide, methylamine, and t-butylamine in dioxane. The substituent effect was investigated at 30.0 ± 0.1 °C. The activation entropy was also studied, and negative ΔS≠ values were obtained. Configuration inversions were observed in the substitution reactions. This result is in conformity with the SN2 mechanism. [Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements for the following free supplemental resource: Characterization of -(p-Substituted-arylsulfinyl)phthalimides 1a–b.]
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