Nrf2 and the promotion of atherosclerosis:lessons to be learned

Abstract,...it seems clear that Nrf2 expression can promote atherosclerosis via systemic and/or vascular local effects... despite its antioxidant actions. Therefore, should the strategy to boost endogenous antioxidant protection via Nrf2 expression be abandoned?-Keywords: antioxidant geneatherosclerosisinflammationlipid n Nrf2oxidative stress