Visible Light Photocatalytic Reduction of O‐Thiocarbamates: Development of a Tin‐Free Barton–McCombie Deoxygenation Reaction

Abstract The Barton–McCombie deoxygenation is one of the most important transformations in the toolbox of organic chemists which has been the subject of a number of methodological developments. In this study, we report a photocatalyzed redox deoxygenation of secondary and tertiary alcohols from thiocarbamate precursors under visible light activation. The iridium complex Ir(ppy) 3 proved to be the most efficient catalyst in the presence of Hünig’s base as sacrifial electron donor. A mechanistic investigation is presented based on fluorescence quenching experiments and cyclic voltammetry. magnified image