Collagen Matrix (DuraGen) in Dural Repair: Analysis of a New Modified Technique

假性脑膜瘤 医学 外科 脑脊液 脑脊液漏 腰椎 纤维蛋白胶 脑脊液鼻漏 并发症 病理 鼻漏
作者
Pradeep K Narotam,Sunil José,Narendra Nathoo,Charles Taylon,Yashail Y. Vora
出处
期刊:Spine [Lippincott Williams & Wilkins]
卷期号:29 (24): 2861-2867 被引量:177
标识
DOI:10.1097/01.brs.0000148049.69541.ad
摘要

Retrospective review of 110 patients undergoing spinal dural repair and regeneration using an onlay, suture-free, 3-dimensional-collagen matrix graft (DuraGen) over an 8-year period (1995-2003).Technique appraisal of collagen matrix to repair spinal dura following incidental durotomy, spinal tumor surgery, and trauma.Traditional methods of spinal dural repair following incidental durotomy involve tedious attempts at primary watertight suture with a 5% to 10% failure rate. Dural injury occurs after trauma, or dural excision may be required after tumor resection. Collagen matrix is a newer development in collagen sponge.The clinical and demographic data included diagnosis, type and site of surgery, infection risk, size of defect, use of lumbar drains, closed suction subfascial drains, and adverse events. The primary endpoints of graft failure were cerebrospinal fluid leak and pseudomeningocele formation. Neurosurgical wound infection rates were determined.Collagen matrix was used (n = 110) in the following conditions: degenerative (69), pseudomeningocele formation repair (4), tumors (14), trauma (13), and congenital (5). There were 15 cervical (10 anterior), 21 thoracic (3 anterior), and 71 lumbar (all posterior) surgeries. Fibrin glue was used in 7.3%, subfascial drains in 82%, and lumbar drainage in 2.7%. Overall, cerebrospinal fluid leaks occurred in 2.7%. The 2 pseudomeningocele formations (3.2%) resolved at 3 months. There were 2 wound infections. In the subgroup with incidental durotomy (n = 69), failure of cerebrospinal fluid containment occurred in 4.3% [1 cerebrospinal fluid leak (1.4%), 2 pseudomeningocele formations (2.9%)].Collagen matrix was successful in cerebrospinal fluid containment in > 95% of patients requiring dural repair following anterior and posterior spinal surgery. Subfascial drains were safe. Routine lumbar drains are not required but are recommended for repair of established pseudomeningocele formations.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
斯文败类应助青野采纳,获得10
刚刚
1秒前
2秒前
2秒前
lulu8809完成签到,获得积分10
2秒前
胡图图完成签到,获得积分10
3秒前
张天宝真的爱科研完成签到,获得积分10
3秒前
SYLH应助wit采纳,获得20
3秒前
高高的蓝天完成签到 ,获得积分10
4秒前
云横秦岭家何在完成签到,获得积分10
4秒前
6秒前
凌代萱完成签到 ,获得积分10
6秒前
7秒前
7秒前
mmm完成签到,获得积分20
10秒前
powell应助喜喵喵采纳,获得10
11秒前
高手发布了新的文献求助10
11秒前
12秒前
gsq发布了新的文献求助30
13秒前
14秒前
香蕉妙菱发布了新的文献求助10
15秒前
深情安青应助wwwstt采纳,获得10
16秒前
易酰水烊酸应助苏苏采纳,获得10
17秒前
17秒前
18秒前
英姑应助小刘采纳,获得10
18秒前
李彪发布了新的文献求助30
18秒前
开心每一天完成签到 ,获得积分10
19秒前
星辰大海应助高手采纳,获得10
19秒前
温柔的姿完成签到,获得积分10
20秒前
传奇3应助gj采纳,获得10
25秒前
XYX关闭了XYX文献求助
33秒前
曲奇吐司完成签到,获得积分10
37秒前
FashionBoy应助Sijie采纳,获得10
39秒前
dong应助夏木夏采纳,获得10
40秒前
美好二娘完成签到 ,获得积分10
42秒前
量子星尘发布了新的文献求助10
44秒前
唐慢慢发布了新的文献求助10
44秒前
ding应助猪猪hero采纳,获得10
44秒前
朴素若枫完成签到,获得积分10
45秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989242
求助须知:如何正确求助?哪些是违规求助? 3531393
关于积分的说明 11253753
捐赠科研通 3270010
什么是DOI,文献DOI怎么找? 1804868
邀请新用户注册赠送积分活动 882084
科研通“疑难数据库(出版商)”最低求助积分说明 809136