Development of evaluation system for bioactive substances using human artificial chromosome-mediated osteocalcin gene expression

Journal Article Development of evaluation system for bioactive substances using human artificial chromosome-mediated osteocalcin gene expression Get access Yusuke Takahashi, Yusuke Takahashi 1Department of Molecular Biology, School of Life Sciences, Faculty of Medicine, Tottori University, Nishi-cho, Yonago, 683-8503; 2Department of Applied Biotechnology, Food Developing Laboratory, Tottori Institute of Industrial Technology, 2023-3 Nakano-cho, Sakaiminato, 684-0041; 3Department of Molecular Cell Genetics, Human Genome Sciences, and Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medicine, Tottori University, Nishi-cho, Yonago, 683-8503; and 4Tottori University Chromosome Engineering Research Center, Nishi-cho, Yonago, 683-8503, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Saori Tsuji, Saori Tsuji 1Department of Molecular Biology, School of Life Sciences, Faculty of Medicine, Tottori University, Nishi-cho, Yonago, 683-8503; 2Department of Applied Biotechnology, Food Developing Laboratory, Tottori Institute of Industrial Technology, 2023-3 Nakano-cho, Sakaiminato, 684-0041; 3Department of Molecular Cell Genetics, Human Genome Sciences, and Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medicine, Tottori University, Nishi-cho, Yonago, 683-8503; and 4Tottori University Chromosome Engineering Research Center, Nishi-cho, Yonago, 683-8503, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Yasuhiro Kazuki, Yasuhiro Kazuki 1Department of Molecular Biology, School of Life Sciences, Faculty of Medicine, Tottori University, Nishi-cho, Yonago, 683-8503; 2Department of Applied Biotechnology, Food Developing Laboratory, Tottori Institute of Industrial Technology, 2023-3 Nakano-cho, Sakaiminato, 684-0041; 3Department of Molecular Cell Genetics, Human Genome Sciences, and Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medicine, Tottori University, Nishi-cho, Yonago, 683-8503; and 4Tottori University Chromosome Engineering Research Center, Nishi-cho, Yonago, 683-8503, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Makoto Noguchi, Makoto Noguchi 1Department of Molecular Biology, School of Life Sciences, Faculty of Medicine, Tottori University, Nishi-cho, Yonago, 683-8503; 2Department of Applied Biotechnology, Food Developing Laboratory, Tottori Institute of Industrial Technology, 2023-3 Nakano-cho, Sakaiminato, 684-0041; 3Department of Molecular Cell Genetics, Human Genome Sciences, and Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medicine, Tottori University, Nishi-cho, Yonago, 683-8503; and 4Tottori University Chromosome Engineering Research Center, Nishi-cho, Yonago, 683-8503, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Ichiro Arifuku, Ichiro Arifuku 1Department of Molecular Biology, School of Life Sciences, Faculty of Medicine, Tottori University, Nishi-cho, Yonago, 683-8503; 2Department of Applied Biotechnology, Food Developing Laboratory, Tottori Institute of Industrial Technology, 2023-3 Nakano-cho, Sakaiminato, 684-0041; 3Department of Molecular Cell Genetics, Human Genome Sciences, and Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medicine, Tottori University, Nishi-cho, Yonago, 683-8503; and 4Tottori University Chromosome Engineering Research Center, Nishi-cho, Yonago, 683-8503, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Yukihiro Umebayashi, Yukihiro Umebayashi 1Department of Molecular Biology, School of Life Sciences, Faculty of Medicine, Tottori University, Nishi-cho, Yonago, 683-8503; 2Department of Applied Biotechnology, Food Developing Laboratory, Tottori Institute of Industrial Technology, 2023-3 Nakano-cho, Sakaiminato, 684-0041; 3Department of Molecular Cell Genetics, Human Genome Sciences, and Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medicine, Tottori University, Nishi-cho, Yonago, 683-8503; and 4Tottori University Chromosome Engineering Research Center, Nishi-cho, Yonago, 683-8503, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Tomoko Nakanishi, Tomoko Nakanishi 1Department of Molecular Biology, School of Life Sciences, Faculty of Medicine, Tottori University, Nishi-cho, Yonago, 683-8503; 2Department of Applied Biotechnology, Food Developing Laboratory, Tottori Institute of Industrial Technology, 2023-3 Nakano-cho, Sakaiminato, 684-0041; 3Department of Molecular Cell Genetics, Human Genome Sciences, and Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medicine, Tottori University, Nishi-cho, Yonago, 683-8503; and 4Tottori University Chromosome Engineering Research Center, Nishi-cho, Yonago, 683-8503, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Mitsuo Oshimura, Mitsuo Oshimura 1Department of Molecular Biology, School of Life Sciences, Faculty of Medicine, Tottori University, Nishi-cho, Yonago, 683-8503; 2Department of Applied Biotechnology, Food Developing Laboratory, Tottori Institute of Industrial Technology, 2023-3 Nakano-cho, Sakaiminato, 684-0041; 3Department of Molecular Cell Genetics, Human Genome Sciences, and Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medicine, Tottori University, Nishi-cho, Yonago, 683-8503; and 4Tottori University Chromosome Engineering Research Center, Nishi-cho, Yonago, 683-8503, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Kenzo Sato Kenzo Sato * 1Department of Molecular Biology, School of Life Sciences, Faculty of Medicine, Tottori University, Nishi-cho, Yonago, 683-8503; 2Department of Applied Biotechnology, Food Developing Laboratory, Tottori Institute of Industrial Technology, 2023-3 Nakano-cho, Sakaiminato, 684-0041; 3Department of Molecular Cell Genetics, Human Genome Sciences, and Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medicine, Tottori University, Nishi-cho, Yonago, 683-8503; and 4Tottori University Chromosome Engineering Research Center, Nishi-cho, Yonago, 683-8503, Japan *Kenzo Sato, Department of Molecular Biology, School of Life Sciences, Faculty of Medicine, Tottori University, Yonago, 683-8503, Japan, Tel: +81 859 38 6201, Fax: +81 859 38 6200, email: kensato@med.tottori-u.ac.jp Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Biochemistry, Volume 148, Issue 1, July 2010, Pages 29–34, https://doi.org/10.1093/jb/mvq030 Published: 17 March 2010 Article history Received: 22 February 2010 Accepted: 08 March 2010 Published: 17 March 2010