Catalyst‐Triggered Highly Selective C−S and C−Se Bond Formation by C−H Activation

Abstract Nickel or iron salts catalyzing the selective synthesis of 3,3‐indolyl disulfide (diselenide) and 3,3‐indolyl thioether (selenide) directly from indole through C−H activation are reported. The effect of iodine element was beneficial in the novel metal‐catalyzed circulation system. A wide variety of functional groups could be tolerated under the reaction conditions.