预酸化
半胱氨酸
药物发现
蛋白质功能
计算生物学
生物
生物信息学
生物化学
酶
基因
作者
Yan Xu,Zu Wang,Chunhui Li,Kuo‐Chen Chou
出处
期刊:Medicinal Chemistry
[Bentham Science Publishers]
日期:2017-08-02
卷期号:13 (6)
被引量:122
标识
DOI:10.2174/1573406413666170419150052
摘要
Background: Occurring at the cysteine residue in the C-terminal of a protein, prenylation is a special kind of post-translational modification (PTM), which may play a key role for statin in altering immune function. Therefore, knowledge of the prenylation sites in proteins is important for drug development as well as for in-depth understanding the biological process concerned. Keywords: Autoimmune disease, cysteine prenylation, protein C-terminal, PseAAC, SVM, web-server.
科研通智能强力驱动
Strongly Powered by AbleSci AI