清脆的
核糖核酸
计算生物学
串联
计算机科学
生物
基因
遗传学
工程类
航空航天工程
作者
Tina Y. Liu,Gavin J. Knott,Dylan C. J. Smock,John J. Desmarais,Sungmin Son,Abdul Bhuiya,Shrutee Jakhanwal,Noam Prywes,Shreeya Agrawal,María Díaz de León Derby,Neil A. Switz,Maxim Armstrong,Andrew R. Harris,Emeric Charles,Brittney W. Thornton,Parinaz Fozouni,Jeffrey Shu,Stephanie I. Stephens,G. Renuka Kumar,Chunyu Zhao
出处
期刊：Cold Spring Harbor Laboratory - medRxiv
日期：2021-03-24
被引量：5
标识
DOI：10.1101/2021.03.19.21253328
摘要
Direct, amplification-free detection of RNA has the potential to transform molecular diagnostics by enabling simple on-site analysis of human or environmental samples. CRISPR-Cas nucleases offer programmable RNA-guided recognition of RNA that triggers cleavage and release of a fluorescent reporter molecule
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