霍夫迈斯特系列
化学
系列(地层学)
生物高聚物
生化工程
纳米技术
盐(化学)
有机化学
材料科学
聚合物
古生物学
工程类
生物
作者
Marcello G. Cacace,Ehud M. Landau,Jeremy J. Ramsden
出处
期刊:Quarterly Reviews of Biophysics
[Cambridge University Press]
日期:1997-08-01
卷期号:30 (3): 241-277
被引量:947
标识
DOI:10.1017/s0033583597003363
摘要
Advances in experimental and computational methodologies have led to a recent renewed interest in the Hofmeister series and its molecular origins. New results are surveyed and assessed. Insights into the underlying mechanisms have been gained, although deeper molecular understanding still seems to be elusive. The principal reason appears to be that the Hofmeister series emerges from a combination of a general effect of cosolutes (salts, etc.) on solvent structure, and of specific interactions between the cosolutes and the solute (protein or other biopolymer). Hence every system needs to be studied individually in detail, a state of affairs which is likely to continue for some time. A deeper understanding of the Hofmeister series can be an extraordinarily valuable guide to designing experiments, including not only those probing the series per se, but also those designed to elucidate the adsorption, aggregation and stabilization phenomena which underlie so many biological events. The aim of this review is to provide an up-to-date framework to guide such understanding, consolidating recent advances in the many fields on which the Hofmeister series impinges.
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