Synthesis of a novel cyclopropyl phosphonate nucleotide as a phosphate mimic
膦酸盐
磷酸盐
化学
核苷酸
立体化学
组合化学
有机化学
生物化学
基因
作者
Erich Altenhofer,Michael J. Lawler,Pankaj Kumar,Leo A. Joyce,Matthew Fowler-Watters,Tao Pei,Zhen Li
出处
期刊:Chemical Communications [The Royal Society of Chemistry] 日期:2021-01-01卷期号:57 (55): 6808-6811被引量:6
标识
DOI:10.1039/d1cc02328d
摘要
A novel cyclopropanation has been demonstrated by tuning the electronics of the substrate, allowing for conversion of the highly stable 1,4-adduct to the desired cyclopropane.