SABR波动模型
医学
离格
放射外科
放射治疗
背向效应
肺癌
重症监护医学
肿瘤科
外科
免疫疗法
内科学
癌症
经济
金融经济学
波动性(金融)
随机波动
作者
Castalia Fernández,Arturo Navarro-Martín,A. Bobo,Joaquín J. Cabrera-Rodríguez,Patricia Calvo,Rodolfo Chicas-Sett,J. Luna,N. Rodriguez De Dios,Felipe Couñago
出处
期刊:World journal of clinical oncology
[Baishideng Publishing Group Co (World Journal of Clinical Oncology)]
日期:2022-02-24
卷期号:13 (2): 101-115
被引量:1
标识
DOI:10.5306/wjco.v13.i2.101
摘要
Stereotactic ablative body radiotherapy (SABR) is an effective technique comparable to surgery in terms of local control and efficacy in early stages of non-small cell lung cancer (NSCLC) and pulmonary metastasis. Several fractionation schemes have proven to be safe and effective, including the single fraction (SF) scheme. SF is an option cost-effectiveness, more convenience and comfortable for the patient and flexible in terms of its management combined with systemic treatments. The outbreak of the severe acute respiratory syndrome coronavirus 2 pandemic has driven this not new but underutilized paradigm, recommending this option to minimize patients' visits to hospital. SF SABR already has a long experience, strong evidence and sufficient maturity to reliably evaluate outcomes in peripheral primary NSCLC and there are promising outcomes in pulmonary metastases, making it a valid treatment option; although its use in central locations, synchronous and recurrencies tumors requires more prospective safety and efficacy studies. The SABR radiobiology study, together with the combination with systemic therapies, (targeted therapies and immunotherapy) is a direction of research in both advanced disease and early stages whose future includes SF.
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