免疫系统
医学
机制(生物学)
免疫学
免疫功能障碍
重症监护医学
哲学
认识论
作者
Ruchi Badoni Semwal,Ruchi Badoni Semwal,Jan Lehmann,Deepak Kumar Semwal
标识
DOI:10.1016/j.intimp.2022.108859
摘要
A strong immune system is a primary requirement to keep the body safe from different ailments and infections. A human knowingly or unknowingly often comes to the exposure of many foreign substances such as pollutants, chemicals, metals and drugs that affect the immune system. Though some of these substances are known to exert immunotoxicity, their precise role as immunotoxicant is still unidentified, hence, the testing of these substances has to be taken into account. The present manuscript aimed to explore the mechanism behind immunotoxicity, biomarkers involved, manifestations, testing of immunotoxicity and its management.Relevant literature on immunotoxicity, collected from online scientific databases like Scopus, PubMed and Google Scholar, was rigorously reviewed.Earlier reports showed that immunotoxic effects of chemicals and pharmaceuticals may cause various health problems including allergic reactions, skin disorders, respiratory infections, gastrointestinal problems, and autoimmune disorders. If diagnosed in time, many of these conditions can be managed with the help of existing treatments although the complete treatment is sometimes a big challenge.Based on the review of available literature, it can be concluded that immunotoxicity is one of the key factors responsible for several infectious diseases, autoimmune disorders and even cancers. Hence, the requirement of advanced diagnostic tools and established treatments for immunotoxicity is highly recommended.
科研通智能强力驱动
Strongly Powered by AbleSci AI