奥拉帕尼
医学
内科学
安慰剂
PARP抑制剂
肺癌
肿瘤科
放化疗
癌症
聚ADP核糖聚合酶
病理
酶
生物化学
化学
替代医学
聚合酶
作者
Penella J. Woll,Piers Gaunt,Sarah Danson,N. Steele,Samreen Ahmed,C Mulatero,Riyaz Shah,Jaishree Bhosle,Elizabeth Hodgkinson,Ben Watkins,Lucinda Billingham
出处
期刊:Lung Cancer
[Elsevier BV]
日期:2022-07-15
卷期号:171: 26-33
被引量:28
标识
DOI:10.1016/j.lungcan.2022.07.007
摘要
Small cell lung cancer (SCLC) responds well to chemoradiotherapy but frequently relapses. Here, we evaluate activity and safety of the poly (adenosine diphosphate (ADP)-ribose) polymerase (PARP) inhibitor olaparib as maintenance treatment for patients with chemoresponsive SCLC.
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