Mechanochemical synthesis of (4S)-N-alkyl-4,5-bis-sulfooxypentanamideviaa one-pot sequential aminolysis-sulfation reaction of (S)-γ-hydroxymethyl-γ-butyrolactone (2H-HBO)

The bio-based platform (S)-γ-hydroxymethyl-γ-butyrolactone, whose sustainable kiloscale-synthesis from cellulose-derived levoglucosenone has been validated, is valorized into new potential bio-based surfactants mechano-synthesized in solventless conditions.