Medical Treatment and Prevention of Urinary Stone Disease

The pathophysiology underlying urinary stone formation remains an area of active investigation. There are many pharmacotherapies aimed at optimizing metabolic factors and reducing urinary supersaturation of stone components that play an important role in urinary stone prevention. In addition, medical expulsive therapy for ureteral stones and medical dissolution therapy for uric acid–based urinary stones are helpful treatment tools and are used alongside surgical treatments in the management of urinary stones.