糖基化
靶向给药
化学
药物输送
药品
计算生物学
药物发现
药理学
生物化学
生物
有机化学
作者
Fang Chen,Gangliang Huang
标识
DOI:10.1016/j.ejmech.2019.111612
摘要
Sugar, as a carrier of human energy and an important bioinformatics molecule, plays a vital role in many important physiological processes, and can control the transmission of bioinformatics by specific recognition with biological molecules such as proteins. Herein, the mechanism of glycosylation-targeted drug delivery was described, various glycosylation methods were summarized, and the applications of glycosylation-targeted drug delivery in liver targeting, brain targeting and lung targeting were discussed. At the same time, the problems of glycosylation targeted drug delivery were suggested, and the application prospects of glycosylation targeting drug delivery were expected.
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