Global prevalence of irritable bowel syndrome according to Rome III or IV criteria: a systematic review and meta-analysis

医学 肠易激综合征 荟萃分析 胃肠病学 内科学
作者
Priya Oka,Heather Parr,Brigida Barberio,Christopher J. Black,Edoardo Savarino,Alexander C. Ford
出处
期刊:The Lancet Gastroenterology & Hepatology [Elsevier]
卷期号:5 (10): 908-917 被引量:598
标识
DOI:10.1016/s2468-1253(20)30217-x
摘要

Background Irritable bowel syndrome (IBS) is one of the most common functional bowel disorders, but community prevalence appears to vary widely between different countries. This variation might be due to the fact that previous cross-sectional surveys have neither applied uniform diagnostic criteria nor used identical methodology, rather than being due to true global variability. We aimed to determine the global prevalence of IBS. Methods We did a systematic review and meta-analysis of data from all population-based studies using relatively uniform methodology and using only the most recent iterations of the Rome criteria (Rome III and IV). We searched MEDLINE, Embase, and Embase Classic (from Jan 1, 2006, to April 30, 2020) to identify cross-sectional surveys reporting the prevalence of IBS in adults (≥90% of participants aged ≥18 years) according to the Rome III or Rome IV criteria. We also hand-searched a selection of conference proceedings for relevant abstracts published between 2006 and 2019. We extracted prevalence data for all studies, according to the criteria used to define the presence of IBS. We did a meta-analysis to estimate pooled prevalence rates, according to study location and certain other characteristics (eg, sex and IBS subtype). Findings We identified 4143 citations, of which 184 studies appeared relevant. 57 of these studies were eligible, and represented 92 separate adult populations, comprising 423 362 participants. The pooled prevalence of IBS in 53 studies that used the Rome III criteria, from 38 countries and comprising 395 385 participants, was 9·2% (95% CI 7·6–10·8; I2=99·7%). By contrast, pooled IBS prevalence among six studies that used the Rome IV criteria, from 34 countries and comprising 82 476 individuals, was 3·8% (95% CI 3·1–4·5; I2=96·6%). IBS with mixed bowel habit (IBS-M) was the most common subtype with the Rome III criteria, reported by 33·8% (95% CI 27·8–40·0; I2=98·1%) of people fulfilling criteria for IBS (ie, 3·7% [2·6–4·9] of all included participants had IBS-M), but IBS with diarrhoea (IBS-D) was the most common subtype with the Rome IV criteria (reported by 31·5% [95% CI 23·2–40·5; I2=98·1% 61·6%] of people with IBS, corresponding to 1·4% [0·9–1·9] of all included participants having IBS-D). The prevalence of IBS was higher in women than in men (12·0% [95% CI 9·3–15·0] vs 8·6% [6·3–11·2]; odds ratio 1·46 [95% CI 1·33–1·59]). Prevalence varied substantially between individual countries, and this variability persisted even when the same diagnostic criteria were applied and identical methodology was used in studies. Interpretation Even when uniform symptom-based criteria are applied, based on identical methodology, to define the presence of IBS, prevalence varies substantially between countries. Prevalence was substantially lower with the Rome IV criteria, suggesting that these more restrictive criteria might be less suitable than Rome III for population-based epidemiological surveys. Funding None.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
cindywu发布了新的文献求助10
1秒前
白先生完成签到 ,获得积分10
2秒前
二哥和他的长毛黄完成签到,获得积分10
3秒前
3秒前
3秒前
科研通AI2S应助refraincc采纳,获得10
4秒前
5秒前
官官发布了新的文献求助10
6秒前
555557应助年轻的烨华采纳,获得10
6秒前
9秒前
hjjjjj1发布了新的文献求助10
9秒前
11秒前
冬瓜熊发布了新的文献求助10
11秒前
白桥发布了新的文献求助10
12秒前
13秒前
sjie完成签到 ,获得积分10
14秒前
平淡的凝竹完成签到,获得积分10
15秒前
林正心发布了新的文献求助20
15秒前
hjjjjj1完成签到,获得积分10
16秒前
付其喜完成签到,获得积分10
16秒前
阿航发布了新的文献求助30
16秒前
Gloria完成签到,获得积分10
18秒前
pluto应助believe采纳,获得10
18秒前
18秒前
18秒前
18秒前
臧佳莹发布了新的文献求助10
19秒前
小胡完成签到,获得积分10
19秒前
风中亦旋完成签到,获得积分10
21秒前
赘婿应助Pom采纳,获得10
23秒前
CaoRouLi发布了新的文献求助10
23秒前
阿航完成签到,获得积分20
23秒前
橘子发布了新的文献求助10
24秒前
24秒前
www发布了新的文献求助10
25秒前
NexusExplorer应助小豆芽采纳,获得10
25秒前
11发布了新的文献求助10
26秒前
28秒前
liangye2222发布了新的文献求助10
29秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3988975
求助须知:如何正确求助?哪些是违规求助? 3531316
关于积分的说明 11253424
捐赠科研通 3269917
什么是DOI,文献DOI怎么找? 1804830
邀请新用户注册赠送积分活动 882063
科研通“疑难数据库(出版商)”最低求助积分说明 809068