Endoscopic approach to early gastric cancer in older adults

Considering the epidemiological features of gastric cancer in older adults, as reviewed by Saif et al. [ [1] Saif M.W. Makrilia N. Zalonis A. Merikas M. Syrigos K. Gastric cancer in the elderly: an overview. Eur J Surg Oncol. 2010 Aug; 36 ([Epub 2010 Jun 9. Review. PubMed PMID: 20542657]): 709-717https://doi.org/10.1016/j.ejso.2010.05.023 Abstract Full Text Full Text PDF PubMed Scopus (108) Google Scholar ], data arising from both high- and low-prevalence areas reveal a male predominance in older patients. This is in contrast to younger patients (<40 years old) where the gender ratio has been reported to be closer to 1:1 with a significant number of studies reporting a female predominance [ 1 Saif M.W. Makrilia N. Zalonis A. Merikas M. Syrigos K. Gastric cancer in the elderly: an overview. Eur J Surg Oncol. 2010 Aug; 36 ([Epub 2010 Jun 9. Review. PubMed PMID: 20542657]): 709-717https://doi.org/10.1016/j.ejso.2010.05.023 Abstract Full Text Full Text PDF PubMed Scopus (108) Google Scholar , 2 Medina-Franco H. Heslin M.J. Cortes-Gonzalez R. Clinicopathological characteristics of gastric carcinoma in young and elderly patients: a comparative study. Ann Surg Oncol. 2000; 7 ([PubMed PMID: 10947020]): 515-519 Crossref PubMed Scopus (87) Google Scholar , 3 Kunisaki C. Akiyama H. Nomura M. Matsuda G. Otsuka Y. Ono H.A. et al. Clinicopathological features of gastric carcinoma in younger and middle-aged patients: a comparative study. J Gastrointest Surg. 2006 Jul-Aug; 10 ([PubMed PMID: 16843873]): 1023-1032 Crossref PubMed Scopus (33) Google Scholar ]. In addition, a few studies have pointed out the absence of a positive family history in most older adults gastric cancer patients [ [1] Saif M.W. Makrilia N. Zalonis A. Merikas M. Syrigos K. Gastric cancer in the elderly: an overview. Eur J Surg Oncol. 2010 Aug; 36 ([Epub 2010 Jun 9. Review. PubMed PMID: 20542657]): 709-717https://doi.org/10.1016/j.ejso.2010.05.023 Abstract Full Text Full Text PDF PubMed Scopus (108) Google Scholar ].