伤害
材料科学
聚集诱导发射
纳米技术
计算机科学
化学
光学
物理
受体
生物化学
荧光
作者
Li Zhou,Shi-Rui Zhang,Jia‐Qin Yang,Jing‐Yu Mao,Yi Ren,Haiquan Shan,Zong‐Xiang Xu,Ye Zhou,Su‐Ting Han
出处
期刊:Nanoscale
[Royal Society of Chemistry]
日期:2019-12-17
卷期号:12 (3): 1484-1494
被引量:31
摘要
Artificial limbs have been widely investigated in the past several decades, and multifuncional bionic limbs have already been constructed. However, due the lack of nociceptive systems, amputees still cannot feel ubiquitous noxious stimuli through bionic limbs. The construction of artificial nociceptors can bring bionic limbs closer to real flesh and bone. In daily life, UV irradiation is an invisible potential noxious stimulus to human skin and eyes. Furthermore, it is well known that the synthetic polymers widely used in bionic limbs can be degraded by UV radiation, accelerating their aging. Based on the above, UV damage-sensing nociceptors could be a feasible strategy to solve these existing problems. Here, azobenzene-functionalized gold nanoparticles (Azo-Au NPs) are embedded in insulating poly(methyl methacrylate) (PMMA) to construct a two-terminal memristor. With UV irradiation as a light damage medium, major nociceptive behaviors such as "threshold", "relaxation" and "sensitization" are successfully emulated, demonstrating its potential application as a nociceptive system.
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