自愈水凝胶
细胞包封
生物加工
明胶
组织工程
泊洛沙姆
生物相容性
壳聚糖
透明质酸
聚乙二醇
丝素
封装(网络)
3D生物打印
琼脂糖
化学
材料科学
纳米技术
生物医学工程
聚合物
高分子化学
共聚物
丝绸
复合材料
计算机科学
色谱法
有机化学
生物
医学
遗传学
计算机网络
作者
Walter Bonani,Nicola Cagol,Devid Maniglio
标识
DOI:10.1007/978-981-15-3262-7_4
摘要
A wide variety of hydrogels have been proposed for tissue engineering applications, cell encapsulation, and bioinks for bioprinting applications. Cell-laden hydrogel constructs rely on natural hydrogels such as alginate, agarose, chitosan, collagen, gelatin, fibroin, and hyaluronic acid (HA), as well as on synthetic hydrogels such as poloxamers (Pluronics®) and polyethylene glycol (PEG). Alginate has become more and more important in the last years, thanks to the possibility to prepare alginate hydrogels suitable for cell encapsulation mainly because of the mild and reversible cross-linking conditions. In this paper alginate will be described in detail with respect to its chemistry, cross-linking behavior, biocompatibility, manufacturing capacity, and possible modifications.
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