Differential Residual Effects of Zaleplon and Zopiclone on Actual Driving: a Comparison with a Low Dose of Alcohol

Zaleplon 10 mg has no residual effects on driving when taken at bedtime, 10 hours before driving. In contrast, zopiclone 7.5 mg can cause marked residual impairment. Patients should be advised to avoid driving the morning after zopiclone administration.