抗氧化剂
食品科学
维加维斯
化学
丙二醛
功能性食品
超氧化物歧化酶
血脂
高脂血症
抗氧化能力
脂质过氧化
传统医学
生物化学
胆固醇
生物
中医药
医学
内分泌学
替代医学
病理
糖尿病
作者
Fei Yu,Jing Gao,Yong Zeng,Changxiao Liu
摘要
BACKGROUND: Adlay (Coix lacryma-jobi L. subsp. ma-yuen (Romanet) T. Koyama (family Poaceae)) seed has been used as a dietary supplement for its therapeutic effects for thousands of years. This study was designed to investigate the effects of adlay seed oil, obtained by supercritical CO2 extraction, on blood lipids and antioxidant capacity in hyperlipidemic rats. RESULTS: Adlay seed oil could reduce the abdominal fat tissue and low-density lipoprotein concentration, and increase the total antioxidant capacity in hyperlipidemic rats. Adlay seed oil also significantly decreased the malondialdehyde content in serum, and increased serum total superoxide dismutase activity in hyperlipidemic rats. Therefore, the antioxidant mechanism might be related to the scavenging effects of adlay seed oil on reactive oxidative species, especially on the superoxide anion free radical. CONCLUSION: The results showed that adlay seed oil had blood lipid-reducing and antioxidant effects, and could be used as a supplement in healthcare food and drugs for the prevention of chronic diseases (especially artherosclerosis and coronary artery disease). Copyright © 2011 Society of Chemical Industry
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